English name: Thrombin from bovine plasma; Factor IIa
Other names: thromboplastin; blood clotting factor 3; original kinase; clotting factor
Source: bovine plasma
Vitality: 40 ~ 300 NIH units / mg protein
Protein: 40 ~ 60%
. Characters: white or almost white amorphous powder or solid soluble in water, insoluble in organic solvents dry powder in 2 ~ 8 ℃ very stable, valid 3a; aqueous solution at room temperature when exposed to heat inactivate 8h, acid, alkali metal. and other activity decreased by animal plasma separation obtained prothrombin, then thromboplastin and calcium chloride activation from. it is a proteolytic enzyme, plasma soluble fibrinogen activated by thrombin under converted into insoluble fibrin network, blood coagulation. Fibrinogen has six peptide chains, thrombin composition is four from the N-terminal peptide chain cutting certain specific peptide bonds (-Arg-Gly), releasing two A peptide (peptide 19) and two B peptide (peptide 21) and the other two for the N-terminal tyrosine peptide chain did not change .A and B peptides resection, reducing the negative charge of the protein molecule, promoting the fibrin linear polymeric molecules and lateral polymerization, thereby forming a fibrin network structure
Usage: biochemical research can promote the conversion of fibrinogen to fibrin enzyme.
Save: -20 ℃, the shelf life of six years