Product description:

English name: Oligomycin
CAS: 1404-19-9
C45H74O11 = 791.06

Level: BR
Content: ≥98% (TLC)
Melting point: 95 ℃
Characters: macrolide antibody complexes white powder, a class similar to the genus Streptomyces of actinomycetes (Streptomyces diastatochro-mogenes) produced points oligomycin A, B, C, D four kinds of oligonucleotide mildew A prime at 150 ~ 151 ℃ its hexagonal crystal form melts, and also decompose in ethanol ultraviolet absorption peak of 225nm, σ at about 20 000. 25 ℃ Solubility (g / 100ml solvent): 0.002 water; ether 28; benzene 6; ethanol 25; acetic acid 37.5; acetone 85. That oligomycin B 28- oxo Oligomycin A; Oligomycin C ie 12- deoxy Oligomycin A; namely 26- off Oligomycin D methylene oligomycin A, m.p. 116 ~ 119 ℃. Polarimetry 116 ° ~ 119 ° (c = 1.36, chloroform)
Uses: Biochemical studies of energy transfer as inhibitors of oxidative phosphorylation, and the proton pump (H ATP) of Fo portion (H permeable membrane portion) in combination, can specifically inhibit transport of H, it also inhibits ATP synthesis and decomposition can be used in biochemical studies of oxidative phosphorylation inhibitor, the electron transfer can not directly interfere with generation of ATP.
Save: 2 ~ 8 ℃